Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | ALAD | P13716 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547061 | 0.82 | CYP2A6 (0.50) | CYP2A6MAPTSMN1; SMN2LMNACYP17A1 | |
| SCHEMBL7451509 | 0.78 | CYP2A6 (0.56) | CYP2A6SMN1; SMN2CYP17A1ALDH1A1MAPK1 | |
| SCHEMBL8649337 | 0.77 | CYP2A6 (0.60) | CYP2A6CYP17A1ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL1521833 | 0.74 | CYP2A6 (0.47) | CYP2A6CYP17A1 | |
| SCHEMBL28580716 | 0.74 | ALDH1A1 (0.36) | CYP2A6MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4124688 | 0.74 | CYP17A1 (0.46) | CYP2A6MAPTSMN1; SMN2CYP17A1ALDH1A1 | |
| SCHEMBL2950828 | 0.72 | RXRA (0.47) | CYP2A6SMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL6920647 | 0.71 | PTGS1 (0.39) | CYP2A6MAPTSMN1; SMN2LMNAALDH1A1 | |
| Formic Acid SCHEMBL10703550 | 0.70 | CYP2A6 (0.44) | CYP2A6MAPTCYP17A1ALDH1A1MAPK1 | |
| SCHEMBL3127775 | 0.70 | PGR (0.44) | CYP2A6MAPTSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110684-B2 | Diaza-spiro [4.5] decanes useful as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100227862-A1 | DIAZA-SPIRO [4.5] DECANES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227862-A1 | DIAZA-SPIRO [4.5] DECANES USEFUL AS PESTICIDES | DDT, CHRM1, DECR1 | CYP2A6 1484/4885MAPT 4822/4885SMN1; SMN2 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.