SCHEMBL5476754

SCHEMBL5476754

COCc1c(S(C)(=O)=O)ccc(C(=O)C2=C(O)C3CCC(C3)C2=O)c1C

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23061257 0.79
SCHEMBL5481372 0.76
SCHEMBL9657374 0.74 HPD (0.36)
SCHEMBL5473449 0.74 IGF1R (0.33)
SCHEMBL22859634 0.73 RORC (0.30)
SCHEMBL23061243 0.73
SCHEMBL9076561 0.73
SCHEMBL4652934 0.73 MRGPRX1 (0.30)
SCHEMBL4652937 0.73 MRGPRX1 (0.30)
SCHEMBL5470517 0.73 LMNA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070265165-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2007-11-15 US disclosed
US-20070265165-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2007-11-15 US disclosed
US-20070265165-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2007-11-15 US disclosed
US-7265230-B2 For inhibiting undesirable plant growth SYNGENTA PARTICIPATIONS AG (CH) 2007-09-04 US disclosed
US-7265230-B2 For inhibiting undesirable plant growth SYNGENTA PARTICIPATIONS AG (CH) 2007-09-04 US disclosed
US-7265230-B2 For inhibiting undesirable plant growth SYNGENTA PARTICIPATIONS AG (CH) 2007-09-04 US disclosed
EP-1140811-B1 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2006-08-02 EP disclosed
US-20030236167-A1 Novel herbicides SCHAETZER JURGEN (DE) 2003-12-25 US disclosed
US-6599861-B2 Applying to weeds SYNGENTA PARTICIPATIONS AG (CH) 2003-07-29 US disclosed
US-20020165096-A1 Novel herbicides SYNGENTA PARTICIPATIONS AG (CH) 2002-11-07 US disclosed
EP-1140811-A1 NOVEL HERBICIDES Syngenta Participations AG (CH) 2001-10-10 EP disclosed
WO-2000037437-A1 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2000-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165096-A1 Novel herbicides DDT, CYP1B1, CYP1A1 GPR119 698/4885
US-20030236167-A1 Novel herbicides DDT, CYP1B1, CYP1A1 GPR119 698/4885
US-20070265165-A1 NOVEL HERBICIDES DDT, CYP1B1, CYP1A1 GPR119 688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.