Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5473450 | 0.98 | LMNA (0.33) | LMNAALDH1A1MAPK1IGF1RSRC | |
| SCHEMBL5473449 | 0.87 | IGF1R (0.33) | ALDH1A1IGF1RSRCAXLPTK2 | |
| SCHEMBL9078012 | 0.84 | LMNA (0.39) | LMNAALDH1A1TSHRKDM5AKDM5B | |
| SCHEMBL28526677 | 0.83 | ALDH1A1 (0.37) | LMNAALDH1A1MAPK1TSHRBCAT2 | |
| SCHEMBL6605776 | 0.81 | ALDH1A1 (0.36) | LMNAALDH1A1MAPK1BCAT2ALOX15 | |
| SCHEMBL30595097 | 0.80 | ALDH1A1 (0.42) | LMNAALDH1A1MAPK1TSHRBCAT2 | |
| SCHEMBL8138242 | 0.80 | ALDH1A1 (0.42) | LMNAALDH1A1MAPK1TSHRBCAT2 | |
| SCHEMBL9657374 | 0.79 | HPD (0.36) | ALDH1A1PTGS2 | |
| SCHEMBL9448604 | 0.76 | PTGS2 (0.34) | ALDH1A1IGF1RSRCAXLPTK2 | |
| SCHEMBL1358599 | 0.76 | TDP1 (0.44) | LMNAALDH1A1MAPK1TSHRACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11171828-A | — | — | None | — | — | JP | disclosed |
| JP-10095702-A | — | — | None | — | — | JP | disclosed |
| US-20070265165-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-7265230-B2 | For inhibiting undesirable plant growth | SYNGENTA PARTICIPATIONS AG (CH) | 2007-09-04 | — | — | US | disclosed |
| EP-1140811-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-02 | — | — | EP | disclosed |
| US-20030236167-A1 | Novel herbicides | SCHAETZER JURGEN (DE) | 2003-12-25 | — | — | US | disclosed |
| US-6599861-B2 | Applying to weeds | SYNGENTA PARTICIPATIONS AG (CH) | 2003-07-29 | — | — | US | disclosed |
| US-20020165096-A1 | Novel herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2002-11-07 | — | — | US | disclosed |
| EP-1140811-A1 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037437-A1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-29 | — | — | WO | disclosed |
| JP-H11171828-A | SUBSTITUTED BENZENE DERIVATIVE | NISSAN CHEM IND LTD | 1999-06-29 | — | — | JP | disclosed |
| JP-H1095702-A | SUBSTITUTED BENZENE DERIVATIVE | NISSAN CHEM IND LTD | 1998-04-14 | — | — | JP | disclosed |
| EP-0282944-B1 | Pyrazole derivative and herbicide containing it | NISSAN CHEMICAL IND LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5175299-A | Benzoic acid derivatives useful as intermediates for the preparation of herbicidal 4-benzoylpyrazoles | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| US-5094685-A | SUBSTITUTED BENZOYL DERIVATIVES AND SELECTIVE HERBICIDES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| US-4954165-A | Substituted benzoyl derivatives and selective herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4948887-A | FOR UPLAND FIELDS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4885022-A | Herbicidal pyrazole derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0282944-A2 | Pyrazole derivative and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165096-A1 | Novel herbicides | DDT, CYP1B1, CYP1A1 | LMNA 4595/4885ALDH1A1 29/4885MAPK1 837/4885 |
| US-20030236167-A1 | Novel herbicides | DDT, CYP1B1, CYP1A1 | LMNA 4595/4885ALDH1A1 29/4885MAPK1 837/4885 |
| US-20070265165-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | LMNA 4597/4885ALDH1A1 37/4885MAPK1 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.