SCHEMBL547727

SCHEMBL547727

Cc1ccc(C(C=O)(C=O)C=O)c(C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.53
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
NOTUM Q6P988 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GFER P55789 1/20 0.41
METAP2 P50579 1/20 0.40
MCL1 Q07820 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
MAOB P27338 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4238024 0.81 CSNK2A1 (0.57) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL1464091 0.79 CSNK2A1 (0.55) CSNK2A1MEN1KMT2ANOTUMALDH1A1
Hydrochloric Acid SCHEMBL30498667 0.78 CSNK2A1 (0.53) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL24405771 0.76 CSNK2A1 (0.52) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL13898677 0.75 CSNK2A1 (0.50) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL467550 0.73 CSNK2A1 (0.68) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL31627797 0.73 CSNK2A1 (0.68) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL547527 0.73 CSNK2A1 (0.57) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL547662 0.72 ALDH1A1 (0.54) MEN1KMT2AALDH1A1CA12CA1
SCHEMBL1805648 0.72 CSNK2A1 (0.61) CSNK2A1MEN1KMT2ANOTUMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2080750-B1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-07-29 EP claimed
EP-2080750-B1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-07-29 EP disclosed
US-9897913-B2 Radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-02-20 US disclosed
US-20150030980-A1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-01-29 US disclosed
US-8846292-B2 Radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-09-30 US disclosed
US-20120171379-A1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-07-05 US disclosed
US-8110334-B2 Radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-02-07 US disclosed
US-20100047709-A1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
EP-2080750-A1 RADIATION-SENSITIVE COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2009-07-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120171379-A1 RADIATION-SENSITIVE COMPOSITION PARG, RAD51, SRMS CSNK2A1 455/4885MEN1 1441/4885KMT2A 1479/4885
US-20100047709-A1 RADIATION-SENSITIVE COMPOSITION C1S, C9, RAD51 CSNK2A1 532/4885MEN1 1910/4885KMT2A 645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.