Sugi Predict

Sugi Predict / Compounds / SCHEMBL4238024

SCHEMBL4238024

SCHEMBL4238024

Cc1ccc(C(C)(C)C)c(C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CSNK2A1 P68400 1/20 0.57
▸ MRGPRX4 Q96LA9 1/20 0.44
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ NOTUM Q6P988 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ GFER P55789 1/20 0.42
▸ NR1H4 Q96RI1 1/20 0.42
▸ GLRA3 O75311 1/20 0.42
▸ GLRB P48167 1/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ METAP2 P50579 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA4 P22748 1/20 0.41
▸ CA6 P23280 1/20 0.41
▸ MAOB P27338 1/20 0.41
▸ CA5A P35218 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9139315 0.86 CSNK2A1 (0.53) CSNK2A1MRGPRX4MEN1KMT2ANOTUM
SCHEMBL25584048 0.84 CSNK2A1 (0.42) CSNK2A1MRGPRX4MEN1KMT2AALDH1A1
SCHEMBL1464091 0.82 CSNK2A1 (0.55) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL17207216 0.82 L3MBTL1 (0.44) CSNK2A1MRGPRX4MEN1KMT2AALDH1A1
SCHEMBL13898677 0.82 CSNK2A1 (0.50) CSNK2A1MRGPRX4MEN1KMT2ANOTUM
SCHEMBL28286877 0.82 CSNK2A1 (0.42) CSNK2A1MRGPRX4MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL30498667 0.81 CSNK2A1 (0.53) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL547727 0.81 CSNK2A1 (0.53) CSNK2A1MEN1KMT2ANOTUMALDH1A1
SCHEMBL12251298 0.80 TP53 (0.49) MRGPRX4
SCHEMBL19665480 0.80 CA12 (0.55) CSNK2A1MEN1KMT2AALDH1A1GLRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344771-A Quantum dot ink, quantum dot light conversion element and display device 苏州星烁纳米科技有限公司 2024-07-16 — — CN disclosed
US-11433061-B2 Heteroaryl sulfonamides and CCR2/CCR9 CHEMOCENTRYX, INC. (US) 2022-09-06 — — US disclosed
CN-109937323-B Light-absorbing film and backlight unit 富士胶片株式会社 2022-06-24 — — CN disclosed
CN-110494777-B Phosphor-containing film and backlight unit 富士胶片株式会社 2021-10-29 — — CN disclosed
CN-109661610-B Phosphor-containing film and backlight unit 富士胶片株式会社 2021-10-26 — — CN disclosed
CN-110214285-B Wavelength conversion film 富士胶片株式会社 2021-08-03 — — CN disclosed
CN-109964155-B Phosphor-containing film and backlight unit 富士胶片株式会社 2021-07-09 — — CN disclosed
CN-109661598-B Phosphor-containing film and backlight unit 富士胶片株式会社 2021-04-27 — — CN disclosed
US-20200147066-A1 Heteroaryl Sulfonamides and CCR2/CCR9 CHEMOCENTRYX, INC. 2020-05-14 — — US disclosed
US-20170095458-A1 HETEROARYL SULFONAMIDES AND CCR2/CCR9 CHEMOCENTRYX, INC. (US) 2017-04-06 — — US disclosed
US-20140031348-A1 HETEROARYL SULFONAMIDES AND CCR2/CCR9 CHEMOCENTRYX INC (US) 2014-01-30 — — US disclosed
US-20140031348-A1 HETEROARYL SULFONAMIDES AND CCR2/CCR9 CHEMOCENTRYX INC (US) 2014-01-30 — — US disclosed
US-8519135-B2 Heteroaryl sulfonamides and CCR2/CCR9 CHEMOCENTRYX, INC. (US) 2013-08-27 — — US disclosed
US-8519135-B2 Heteroaryl sulfonamides and CCR2/CCR9 CHEMOCENTRYX, INC. (US) 2013-08-27 — — US disclosed
US-8093247-B2 Heteroaryl sulfonamides and CCR2 CHEMOCENTRYX, INC. (US) 2012-01-10 — — US disclosed
US-20110118248-A1 Heteroaryl sulfonamides and CCR2/CCR9 CHEMOCENTRYX, INC. 2011-05-19 — — US disclosed
US-7897627-B2 Heteroaryl derivatives as orexin receptor antagonists HOFFMANN-LA ROCHE INC. (US) 2011-03-01 — — US disclosed
US-20100056509-A1 HETEROARYL SULFONAMIDES AND CCR2 CHEMOCENTRYX, INC. 2010-03-04 — — US disclosed
US-20090163485-A1 HETEROARYL DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2009-06-25 — — US disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11433061-B2 Heteroaryl sulfonamides and CCR2/CCR9 CCR2, CCR9, CCR1 CSNK2A1 776/4885MRGPRX4 97/4885MEN1 4873/4885
US-20100056509-A1 HETEROARYL SULFONAMIDES AND CCR2 CCR2, CXCR2, CCR1 CSNK2A1 580/4885MRGPRX4 115/4885MEN1 4873/4885
US-20090163485-A1 HETEROARYL DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS HCRTR1, HCRTR2, MTNR1A CSNK2A1 2020/4885MRGPRX4 480/4885MEN1 2265/4885
US-20140031348-A1 HETEROARYL SULFONAMIDES AND CCR2/CCR9 CCR2, CCR9, CCR1 CSNK2A1 776/4885MRGPRX4 97/4885MEN1 4873/4885
US-20170095458-A1 HETEROARYL SULFONAMIDES AND CCR2/CCR9 CCR2, CCR9, CCR1 CSNK2A1 776/4885MRGPRX4 97/4885MEN1 4873/4885
US-20200147066-A1 Heteroaryl Sulfonamides and CCR2/CCR9 CCR2, CCR9, CCR1 CSNK2A1 776/4885MRGPRX4 97/4885MEN1 4873/4885
US-20110118248-A1 Heteroaryl sulfonamides and CCR2/CCR9 CCR2, CCR9, CCR1 CSNK2A1 776/4885MRGPRX4 97/4885MEN1 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.