Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13395774 | 0.79 | CA12 (0.32) | ANPEPCA12MMP8CA1CA9 | |
| SCHEMBL5753028 | 0.72 | CA12 (0.40) | CA12MMP8CA1CA9MMP2 | |
| SCHEMBL67648 | 0.72 | CA12 (0.40) | CA12MMP8CA1CA9MMP2 | |
| SCHEMBL21547567 | 0.71 | — | — | |
| SCHEMBL9459111 | 0.69 | CA12 (0.39) | CA12MMP8CA1CA9MMP2 | |
| SCHEMBL9629113 | 0.69 | FDPS (0.42) | ANPEPCA12MMP8CA1MMP2 | |
| SCHEMBL8336668 | 0.67 | CA12 (0.42) | CA12MMP8CA1CA9MMP2 | |
| Phosphoric Acid SCHEMBL1830646 | 0.67 | MMP8 (0.38) | ANPEPCA12MMP8CA1CA9 | |
| Dimethylamine SCHEMBL11688632 | 0.67 | LAP3 (0.41) | ANPEPCA12MMP8CA1CA9 | |
| SCHEMBL731378 | 0.67 | MMP2 (0.39) | ANPEPCA12MMP8CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345294-B1 | DRUGS CONTAINING PLATINUM COMPLEXES | ASTA MEDICA AG (DE) | 1994-04-27 | — | — | EP | claimed |
| US-5256653-A | Pharmaceutical preparations containing platinum complexes/phosphonic acid liquid and processes for their use | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1993-10-26 | — | — | US | claimed |
| US-7662977-B2 | PI-3 kinase inhibitor prodrugs | SEMAFORE PHARMACEUTICALS, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| US-7662977-B2 | PI-3 kinase inhibitor prodrugs | SEMAFORE PHARMACEUTICALS, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| US-20080188423-A1 | PI-3 KINASE INHIBITOR PRODRUGS | SIGNALRX PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188423-A1 | PI-3 KINASE INHIBITOR PRODRUGS | SIGNALRX PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
| US-7396828-B2 | PI-3 kinase inhibitor prodrugs | SEMAFORE PHARMACEUTICALS, INC. (US) | 2008-07-08 | — | — | US | disclosed |
| US-7396828-B2 | PI-3 kinase inhibitor prodrugs | SEMAFORE PHARMACEUTICALS, INC. (US) | 2008-07-08 | — | — | US | disclosed |
| US-20070224115-A1 | Polymeric chelators for radionuclide delivery systems | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-09-27 | — | — | US | disclosed |
| WO-2004089925-A1 | PI-3 KINASE INHIBITOR PRODRUGS | SEMAFORE PHARMACEUTICALS, INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| EP-0345294-B1 | DRUGS CONTAINING PLATINUM COMPLEXES | ASTA MEDICA AG (DE) | 1994-04-27 | — | — | EP | disclosed |
| US-4307038-A | N-Carboxy alkyl amino alkane polyphosphonic acids | BENCKISER-KNAPSACK GMBH (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4230700-A | ADMINISTERING AN ORGANIC MONO- OR DIPHOSPHONATE AND A VITAMIN-D-LIKE ANTIRACHITIC COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| US-4122151-A | Process of stabilization of dibasic calcium phosphate dihydrate against hydrolysis with cyclic aminophosphonic acids | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4117090-A | TOOTHPASTES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117086-A | TOOTHPASTES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4094782-A | PREVENTING SCALE AND DEPOSIT FORMATION | JOH. A. BENCKISER (DT) | 1978-06-13 | — | — | US | disclosed |
| US-4029697-A | ANTISCALING, ANTIDEPOSIT | JOH. A. BENCKISER GMBH (DT) | 1977-06-14 | — | — | US | disclosed |
| US-3979385-A | HEAVY METAL COMPLEXING AGENTS | HENKEL & CIE G.M.B.H. (DT) | 1976-09-07 | — | — | US | disclosed |
| US-3957160-A | Process for the prevention of precipitations in water or aqueous solutions | HENKEL & CIE G.M.B.H. (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188423-A1 | PI-3 KINASE INHIBITOR PRODRUGS | PI4KA, PI4KB, PI4K2B | ANPEP 1597/4885CA12 4757/4885MMP8 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.