Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12023089 | 0.78 | TRPM4 (0.44) | NQO1TRPM4LMNAHTTPTPN22 | |
| SCHEMBL15485758 | 0.77 | NQO1 (0.50) | NQO1TRPM4LMNAHTTPTPN22 | |
| SCHEMBL8865515 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL25485142 | 0.77 | NQO1 (0.44) | NQO1TRPM4LMNAHTTCYP1A2 | |
| SCHEMBL28436429 | 0.77 | ALDH1A1 (0.44) | NQO1TRPM4LMNAHTTPTPN22 | |
| SCHEMBL1852309 | 0.76 | CCR1 (0.47) | LMNAHTTKDM4ETP53PKM | |
| SCHEMBL18685785 | 0.75 | NSD2 (0.54) | PTPN22CYP1A2CYP2A6ALDH1A1HPGD | |
| SCHEMBL24211866 | 0.74 | GPR84 (0.47) | NQO1TRPM4PTPN22ALDH1A1HPGD | |
| SCHEMBL460619 | 0.74 | TRPM4 (0.52) | NQO1TRPM4PTPN22CYP1A2NQO2 | |
| SCHEMBL9742287 | 0.74 | MCL1 (0.50) | NQO1LMNACYP1A2NQO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39663-E1 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes | APPLERA CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
| US-RE39663-E1 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes | APPLERA CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
| EP-1196640-B1 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORP (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1196640-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | Applera Corporation (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001057264-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
| US-6221604-B1 | CONJUGATED TO SUBSTRATES SUCH AS NUCLEOSIDES OR NUCLEOTIDES AND USED AS DETECTION LABELS IN MOLECULAR BIOLOGY EXPERIMENTS; ENERGY TRANSFER DYE | PE CORPORATION | 2001-04-24 | — | — | US | disclosed |