Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.47 |
| ▸ | CCR8 | P51685 | 4/20 | 0.47 |
| ▸ | CCR5 | P51681 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | COMT | P21964 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434393 | 0.77 | CCR1 (0.56) | CCR1CCR8CCR5KDM4EMMP2 | |
| SCHEMBL5478449 | 0.76 | NQO1 (0.46) | KDM4EHTTLMNATP53PKM | |
| SCHEMBL17931878 | 0.74 | LMNA (0.53) | CCR1CCR8CCR5KDM4ECOMT | |
| SCHEMBL29720360 | 0.72 | CCR1 (0.62) | CCR1CCR8CCR5KDM4EMMP2 | |
| SCHEMBL28808993 | 0.72 | CCR1 (0.62) | CCR1CCR8CCR5KDM4EMMP2 | |
| SCHEMBL1853503 | 0.71 | SLC40A1 (0.52) | CCR1CCR8CCR5KDM4EHTT | |
| SCHEMBL11959681 | 0.71 | KDM4E (0.56) | CCR1CCR8CCR5KDM4ECOMT | |
| SCHEMBL20041412 | 0.70 | L3MBTL1 (0.44) | KDM4EHTTSLC6A2L3MBTL1NPC1 | |
| SCHEMBL8344969 | 0.70 | HTT (0.46) | CCR1CCR8CCR5KDM4ECOMT | |
| SCHEMBL170139 | 0.69 | ALDH1A1 (0.59) | CCR1CCR8KDM4ECOMTMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325170-B1 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2014-03-12 | — | — | EP | disclosed |
| EP-2325170-B1 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2014-03-12 | — | — | EP | disclosed |
| US-8658569-B2 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2014-02-25 | — | — | US | disclosed |
| US-8658569-B2 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2014-02-25 | — | — | US | disclosed |
| US-8658569-B2 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2014-02-25 | — | — | US | disclosed |
| US-20120316063-A1 | Substituted Quinolinones Having Herbicidal Action | BASF SE (DE) | 2012-12-13 | — | — | US | disclosed |
| US-20120316063-A1 | Substituted Quinolinones Having Herbicidal Action | BASF SE (DE) | 2012-12-13 | — | — | US | disclosed |
| US-20120316063-A1 | Substituted Quinolinones Having Herbicidal Action | BASF SE (DE) | 2012-12-13 | — | — | US | disclosed |
| US-8329619-B2 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2012-12-11 | — | — | US | disclosed |
| US-8329619-B2 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2012-12-11 | — | — | US | disclosed |
| US-8329619-B2 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2012-12-11 | — | — | US | disclosed |
| EP-2325170-A1 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-2325170-A1 | Substituted quinolinones having herbicidal action | BASF SE (DE) | 2011-05-25 | — | — | EP | disclosed |
| US-20110105329-A1 | Substituted Quinolinones Having Herbicidal Action | BASF SE (DE) | 2011-05-05 | — | — | US | disclosed |
| US-20110105329-A1 | Substituted Quinolinones Having Herbicidal Action | BASF SE (DE) | 2011-05-05 | — | — | US | disclosed |
| US-20110105329-A1 | Substituted Quinolinones Having Herbicidal Action | BASF SE (DE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316063-A1 | Substituted Quinolinones Having Herbicidal Action | DDT, NQO2, CYP1A1 | CCR1 4486/4885CCR8 4709/4885CCR5 4661/4885 |
| US-20110105329-A1 | Substituted Quinolinones Having Herbicidal Action | DDT, NQO2, CYP1A1 | CCR1 4486/4885CCR8 4709/4885CCR5 4661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.