Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490036 | 0.92 | MEN1 (0.55) | MEN1KMT2ASIGMAR1FAAH | |
| SCHEMBL5483514 | 0.92 | MEN1 (0.60) | MEN1KMT2ASIGMAR1FAAHLMNA | |
| SCHEMBL5475896 | 0.90 | SIGMAR1 (0.58) | MEN1KMT2ASIGMAR1FAAHHTR7 | |
| SCHEMBL5486473 | 0.89 | MEN1 (0.62) | MEN1KMT2ASIGMAR1FAAHHTR1A | |
| SCHEMBL5487080 | 0.82 | SIGMAR1 (0.66) | MEN1KMT2ASIGMAR1FAAHLMNA | |
| SCHEMBL5477755 | 0.82 | FAAH (0.57) | MEN1KMT2ASIGMAR1FAAHHTR1A | |
| SCHEMBL5481354 | 0.81 | SIGMAR1 (0.61) | MEN1KMT2ASIGMAR1LMNA | |
| SCHEMBL2175549 | 0.80 | MEN1 (0.48) | MEN1KMT2ASIGMAR1FAAHHTR1A | |
| SCHEMBL27564901 | 0.80 | SIGMAR1 (0.73) | MEN1KMT2ASIGMAR1FAAH | |
| SCHEMBL5480231 | 0.80 | SIGMAR1 (0.54) | MEN1KMT2ASIGMAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | claimed |
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | disclosed |