Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480249 | 0.92 | MEN1 (0.61) | MEN1KMT2ASIGMAR1LMNAFAAH | |
| SCHEMBL5490036 | 0.88 | MEN1 (0.55) | MEN1KMT2ASIGMAR1FAAH | |
| SCHEMBL5489773 | 0.87 | SIGMAR1 (0.53) | MEN1KMT2ASIGMAR1MCHR1FAAH | |
| SCHEMBL5480169 | 0.87 | SIGMAR1 (0.62) | SIGMAR1FAAH | |
| SCHEMBL5475896 | 0.84 | SIGMAR1 (0.58) | MEN1KMT2ASIGMAR1FAAH | |
| SCHEMBL5486473 | 0.83 | MEN1 (0.62) | MEN1KMT2ASIGMAR1LMNAFAAH | |
| SCHEMBL2178351 | 0.81 | FAAH (0.52) | MEN1KMT2ASIGMAR1MCHR1FAAH | |
| SCHEMBL5481359 | 0.79 | SIGMAR1 (0.58) | MEN1KMT2ASIGMAR1FAAH | |
| SCHEMBL5484678 | 0.79 | MEN1 (0.61) | MEN1KMT2ASIGMAR1FAAH | |
| SCHEMBL27564901 | 0.79 | SIGMAR1 (0.73) | MEN1KMT2ASIGMAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | claimed |
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | disclosed |