SCHEMBL5481080

SCHEMBL5481080

O=C(O)C1CCCN1C(=O)c1ccc(-c2ccccc2C(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.52
SLC6A7 Q99884 1/20 0.51
DGAT1 O75907 1/20 0.51
ALDH1A1 P00352 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
TDP1 Q9NUW8 1/20 0.47
GHSR Q92847 1/20 0.47
GYS1 P13807 1/20 0.47
PDK2 Q15119 3/20 0.47
CNR2 P34972 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
FFAR2 O15552 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5036076 0.82 CA2 (0.64) CA2DGAT1ALDH1A1L3MBTL1TDP1
SCHEMBL1750558 0.82 CA2 (0.64) CA2DGAT1ALDH1A1L3MBTL1TDP1
SCHEMBL24313493 0.82 ALDH1A1 (0.56) CA2SLC6A7ALDH1A1L3MBTL1TDP1
SCHEMBL2345865 0.80 MET (0.60) SLC6A7PDK2CNR2
SCHEMBL2345863 0.80 MET (0.60) SLC6A7PDK2CNR2
SCHEMBL13369767 0.80 FFAR2 (0.62) ALDH1A1L3MBTL1FFAR2
SCHEMBL2052708 0.80 ALDH1A1 (0.60) CA2ALDH1A1L3MBTL1TDP1GYS1
SCHEMBL13230 0.79 CA2 (0.67) CA2ALDH1A1L3MBTL1TDP1NPSR1
SCHEMBL13229 0.79 CA2 (0.67) CA2ALDH1A1L3MBTL1TDP1NPSR1
SCHEMBL28789388 0.79 CA2 (0.67) CA2ALDH1A1L3MBTL1TDP1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189754-B2 Pyrrolidine ester derivatives with oxytocin modulating activity APPLIED RESEARCH SYSTEMS ARS HOLDING NV (AN) 2007-03-13 US claimed