Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084601 | 0.95 | TSHR (0.46) | TSHRPGRSRD5A2TP53ALDH1A1 | |
| SCHEMBL25309350 | 0.87 | TSHR (0.50) | TSHRSRD5A2TP53ALDH1A1RARA | |
| SCHEMBL5081784 | 0.87 | TSHR (0.52) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL5568792 | 0.85 | EPHX2 (0.42) | TSHRPGRTP53RARBRARG | |
| SCHEMBL2745792 | 0.84 | PGR (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6939188 | 0.83 | GRIN2D (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5481142 | 0.83 | HIF1A (0.47) | GRIN2BTSHRPGRALDH1A1 | |
| SCHEMBL5141270 | 0.83 | HIF1A (0.47) | GRIN2BTSHRPGRALDH1A1 | |
| SCHEMBL2746653 | 0.82 | PGR (0.40) | PGRHSD11B1RARARARBRARG | |
| SCHEMBL5084654 | 0.81 | TSHR (0.57) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078256-A1 | Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1683822-A1 | PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM | Daicel Chemical Industries, Ltd. (JP) | 2006-07-26 | — | — | EP | disclosed |