Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442187 | 0.89 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4ECA12CA1 | |
| SCHEMBL11196307 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KDM4ECA12CA1 | |
| SCHEMBL8625807 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HSD17B10KDM4ENPC1LMNA | |
| SCHEMBL11031904 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KDM4EGAANPC1 | |
| SCHEMBL4089368 | 0.81 | KMT2A (0.62) | ALDH1A1HSD17B10KDM4EGAANPC1 | |
| SCHEMBL13416408 | 0.81 | KDM1A (0.68) | ALDH1A1HSD17B10KDM4EKDM1AGAA | |
| SCHEMBL8072487 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4ECA12CA1 | |
| SCHEMBL2605790 | 0.79 | KDM4E (0.70) | ALDH1A1HSD17B10KDM4ENPC1MCL1 | |
| SCHEMBL8077720 | 0.79 | KDM4E (0.50) | ALDH1A1HSD17B10KDM4ECA12CA1 | |
| SCHEMBL11197601 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HSD17B10KDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
| EP-1668004-A1 | BENZOXAZOLE ACETONITRILES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026159-A1 | BENZOXAZOLE ACETONITRILES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | disclosed |
| US-5976753-A | COPOLYMER | EASTMAN KODAK COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| US-5922822-A | AN ACRYLATE COPOLYMER CHARGE-CONTROL AGENTS IN ELECTROSTATOGRAPHIC TONERS AND DEVELOPERS | EASTMAN KODAK COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| US-5849449-A | Electrostatographic developer having toner particles containing polymers of (2-cyanoacetamido)phenyl acrylates polymers | EASTMAN KODAK COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5750305-A | Poly (2-(sulfonamidomethylene)-2-cyanoacetamido)phenyl acrylate! charge-control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5739235-A | CHARGE CONTROL AGENTS FOR ELECTROGRAPHY | EASTMAN KODAK COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0068880-B1 | PHOTOGRAPHIC ELEMENTS CAPABLE OF PROVIDING OXOINDOLIZINE AND OXOINDOLIZINIUM DYE COMPOUNDS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-08-07 | — | — | EP | disclosed |
| EP-0068876-B1 | OXOINDOLIZINE AND OXOINDOLIZINIUM DYES AND PROCESSES FOR THEIR PREPARATION | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-04-03 | — | — | EP | disclosed |
| EP-0068876-A1 | Oxoindolizine and oxoindolizinium dyes and processes for their preparation | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | PKD1, PC, GPR119 | ALDH1A1 2797/4885HSD17B10 741/4885KDM4E 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.