Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442187 | 0.87 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL21973109 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HSD17B10KDM4EALOX12RAB9A | |
| SCHEMBL11197601 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HSD17B10KDM4EMAPTLMNA | |
| SCHEMBL2005846 | 0.81 | RAB9A (0.73) | ALDH1A1HSD17B10HPGDALOX12RAB9A | |
| SCHEMBL29528561 | 0.81 | RAB9A (0.73) | ALDH1A1HSD17B10HPGDALOX12RAB9A | |
| SCHEMBL5481312 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10KDM4EHPGDRAB9A | |
| SCHEMBL11419554 | 0.81 | MEN1 (0.57) | ALDH1A1HSD17B10KDM4ENPC1MAPT | |
| SCHEMBL13384689 | 0.80 | ALDH1A1 (0.73) | ALDH1A1HSD17B10KDM4ESMN1; SMN2TSHR | |
| SCHEMBL11144382 | 0.80 | KMT2A (0.70) | ALDH1A1KDM4EHPGDMAPTMAPK1 | |
| SCHEMBL11031904 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| WO-2017106552-A1 | POTENTIATORS OF BETA-LACTAM ANTIBIOTICS AND COMBINATION THERAPY | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-06-22 | — | — | WO | disclosed |
| EP-1664173-B1 | METHOD FOR REDUCING THE ACETALDEHYDE LEVEL IN POLYESTERS | EASTMAN CHEM CO (US) | 2008-06-11 | — | — | EP | disclosed |
| US-5716446-A | PRINTING INK; TONERS; POWDER COATING | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | disclosed |
| US-5698705-A | BASED ON AMINOBENZIMIDAZOLONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
| US-4438092-A | 5-Amino-N-(3-chloro- 2-methyl-, or 2-fluorophenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamides and use as an anti-convulsant | WARNER-LAMBERT COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4346097-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| US-4008262-A | DISPERSE DYE INTERMEDIATE | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |
| US-3954830-A | Yellow methine dyes for hydrophobic textile material | AMERICAN ANILINE PRODUCTS, INC. (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | DDT, ACHE, AHR | ALDH1A1 2254/4885HSD17B10 2974/4885KDM4E 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.