Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | USP8 | P40818 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480716 | 0.81 | ADORA2A (0.56) | KDM4EL3MBTL1HPGDSMN1; SMN2ADORA2A | |
| SCHEMBL5481379 | 0.80 | KDM4E (0.46) | MAPK1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL10757785 | 0.74 | ALDH1A1 (0.46) | MAPK1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL5482010 | 0.70 | LMNA (0.56) | KDM4EHPGDSMN1; SMN2USP8ADORA2A | |
| SCHEMBL31728806 | 0.70 | ALDH1A1 (0.45) | MAPK1KDM4EL3MBTL1HPGDADORA1 | |
| SCHEMBL5483595 | 0.68 | ALDH1A1 (0.45) | MAPK1KDM4EL3MBTL1HPGDADORA2A | |
| SCHEMBL18005940 | 0.67 | MAPK1 (0.43) | MAPK1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL564697 | 0.66 | ALDH1A1 (0.53) | MAPK1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL29539340 | 0.66 | PLA2G2A (0.37) | MAPK1KDM4EUSP8USP7ADORA2A | |
| SCHEMBL642228 | 0.66 | HDAC4 (0.58) | MAPK1KDM4EHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | WYETH | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K6 | MAPK1 28/4885KDM4E 959/4885L3MBTL1 2767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.