Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | PRKACG | P22612 | 1/20 | 0.40 |
| ▸ | PRKACB | P22694 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480716 | 0.81 | ADORA2A (0.56) | LMNASQORADORA2AKDM4EALDH1A1 | |
| SCHEMBL16053280 | 0.78 | ADORA2A (0.44) | LMNAADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL5329331 | 0.77 | ADORA1 (0.56) | ADORA2AADORA1HSD17B10 | |
| SCHEMBL5482017 | 0.76 | LMNA (0.50) | LMNALRRK2ADORA2AKDM4EALDH1A1 | |
| SCHEMBL20568668 | 0.76 | NCF1 (0.49) | LMNASQORADORA2AKDM4EALDH1A1 | |
| SCHEMBL29993462 | 0.75 | LMNA (0.51) | LMNALRRK2ADORA2AKDM4EALDH1A1 | |
| SCHEMBL4436882 | 0.73 | NOS3 (0.50) | LMNAADORA2AALDH1A1TDP1CYP3A4 | |
| SCHEMBL10000551 | 0.72 | TSHR (0.52) | LMNALRRK2SQORADORA2AALDH1A1 | |
| SCHEMBL29589050 | 0.72 | PRKACA (0.44) | LMNAPRKACAPRKACGPRKACBADORA2A | |
| SCHEMBL3073575 | 0.72 | PIK3CD (0.44) | LRRK2PRKACAPRKACGPRKACBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | WYETH | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K6 | LMNA 2130/4885LRRK2 1241/4885SQOR 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.