Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.62 |
| ▸ | SMO | Q99835 | 4/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411010 | 0.80 | MAPK14 (0.73) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL5481692 | 0.78 | MAPK14 (0.77) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL5481697 | 0.78 | MAPK14 (0.71) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL14534470 | 0.73 | MAPK14 (0.67) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL4551323 | 0.73 | MAPK14 (0.72) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL4551331 | 0.73 | MAPK14 (0.71) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL5490044 | 0.71 | MAPK14 (0.74) | MAPK14SMO | |
| SCHEMBL4418530 | 0.70 | MAPK14 (0.61) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL5489948 | 0.69 | MAPK14 (0.48) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL4551322 | 0.67 | MAPK14 (0.61) | MAPK14SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |