Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CIT | O14578 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925812 | 0.78 | MTNR1A (0.54) | KDM4EENPP3ENPP1WNT3AMTNR1A | |
| SCHEMBL20782574 | 0.68 | ENPP3 (0.62) | ENPP3ENPP1WNT3ATLR8GRM2 | |
| SCHEMBL28428417 | 0.66 | ENPP3 (0.62) | KDM4EENPP3ENPP1WNT3ATLR8 | |
| SCHEMBL10157305 | 0.66 | PIK3CA (0.57) | KDM4EENPP3ENPP1MTNR1AMTNR1B | |
| SCHEMBL30440258 | 0.66 | PIK3CA (0.57) | KDM4EMTNR1AMTNR1BMAPK1NPSR1 | |
| SCHEMBL22407440 | 0.64 | ENPP3 (0.56) | KDM4EENPP3ENPP1WNT3AMAPK1 | |
| SCHEMBL16549227 | 0.64 | MAP4K4 (0.50) | KDM4EENPP3ENPP1MAPK1NPSR1 | |
| SCHEMBL20589395 | 0.63 | F2RL1 (0.49) | AR | |
| SCHEMBL24009105 | 0.63 | ENPP3 (0.64) | ENPP3ENPP1WNT3ATLR8GRM2 | |
| SCHEMBL20771286 | 0.63 | ENPP3 (0.43) | ENPP3ENPP1TLR8GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004710-A1 | Antibacterial agents | SMITHKLINE BEECHAM CORPORATION | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004710-A1 | Antibacterial agents | NQO2, NRDC, IFNG | KDM4E 4544/4885ENPP3 676/4885ENPP1 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.