SCHEMBL5481775

SCHEMBL5481775

CCN(Cc1ccc(Oc2ccc3c(c2)S(=O)(=O)NCN3CCF)cc1)S(C)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 17/20 0.49
APLNR P35414 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5485316 0.90 GRIA2 (0.37) GRIA2APLNR
SCHEMBL5482325 0.89 GRIA2 (0.51) GRIA2
SCHEMBL5479962 0.82 GRIA2 (0.52) GRIA2
SCHEMBL5482710 0.80 GRIA2 (0.54) GRIA2
SCHEMBL5475951 0.79 GRIA2 (0.68) GRIA2
SCHEMBL5482327 0.79 GRIA2 (0.39) GRIA2APLNR
SCHEMBL5477044 0.76 GRIA2 (0.49) GRIA2
SCHEMBL5481538 0.76 GRIA2 (0.72) GRIA2
SCHEMBL5481531 0.73 GRIA2 (0.48) GRIA2
SCHEMBL5479896 0.73 GRIA2 (0.48) GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070270415-A1 Benzothiadiazine compounds LESLABORATOIRES SERVIER (FR) 2007-11-22 US disclosed
US-20070106083-A1 Process for preparing 4-aminotetrahydropyran compound and an acid salt thereof, synthetic intermediate thereof and process for preparing the same UBE INDUSTRIES, LTD. (JP) 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070270415-A1 Benzothiadiazine compounds SLC1A1, SLC1A2, SULT2A1 GRIA2 47/4885APLNR 4415/4885
US-20070106083-A1 Process for preparing 4-aminotetrahydropyran compound and an acid salt thereof, synthetic intermediate thereof and process for preparing the same PAH, HPD, REN GRIA2 747/4885APLNR 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.