Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 9/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481775 | 0.90 | GRIA2 (0.49) | GRIA2APLNR | |
| SCHEMBL5482327 | 0.89 | GRIA2 (0.39) | GRIA2APLNR | |
| SCHEMBL5479955 | 0.83 | GRIA2 (0.39) | GRIA2LMNA | |
| SCHEMBL5482709 | 0.81 | LTA4H (0.41) | GRIA2LMNA | |
| SCHEMBL5482325 | 0.79 | GRIA2 (0.51) | GRIA2 | |
| SCHEMBL5477040 | 0.77 | GRIA2 (0.39) | GRIA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5484644 | 0.76 | GRIA2 (0.40) | GRIA2 | |
| SCHEMBL5481528 | 0.73 | GRIA2 (0.39) | GRIA2LMNASMN1; SMN2 | |
| SCHEMBL5479962 | 0.72 | GRIA2 (0.52) | GRIA2 | |
| SCHEMBL5483529 | 0.72 | GRIA2 (0.41) | GRIA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270415-A1 | Benzothiadiazine compounds | LESLABORATOIRES SERVIER (FR) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270415-A1 | Benzothiadiazine compounds | SLC1A1, SLC1A2, SULT2A1 | GRIA2 47/4885APLNR 4415/4885TAS2R14 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.