Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 18/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 17/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.46 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.46 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219981 | 0.80 | ALDH1A1 (0.61) | ADORA1ADORA2AHSD17B10CDK2 | |
| SCHEMBL17610510 | 0.78 | PIM1 (0.53) | ADORA1ADORA2AMAP4K4MAPK8CLK2 | |
| SCHEMBL5482010 | 0.77 | LMNA (0.56) | ADORA1ADORA2AHSD17B10 | |
| SCHEMBL10429370 | 0.75 | ADORA1 (0.54) | ADORA1ADORA2AHSD17B10CHUKCLK4 | |
| SCHEMBL4058635 | 0.75 | CDK5 (0.47) | ADORA1ADORA2AHSD17B10MAPK9CLK4 | |
| SCHEMBL2977679 | 0.75 | ALDH1A1 (0.44) | ADORA1ADORA2AHSD17B10 | |
| SCHEMBL5336780 | 0.75 | ADORA1 (0.55) | ADORA1ADORA2AADORA2B | |
| SCHEMBL1145014 | 0.74 | ADORA1 (0.64) | ADORA1ADORA2AHSD17B10ADORA2BXDH | |
| SCHEMBL5480716 | 0.73 | ADORA2A (0.56) | ADORA1ADORA2AHSD17B10 | |
| SCHEMBL10075618 | 0.73 | CDK5 (0.46) | ADORA1ADORA2AXDHMAPK9CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | WYETH | 2007-12-13 | — | — | US | disclosed |
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K6 | ADORA1 671/4885ADORA2A 1009/4885HSD17B10 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.