Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.38 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567369 | 0.92 | ALDH1A1 (0.46) | ALDH1A1NPC1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL1954208 | 0.83 | KMT2A (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL28584697 | 0.81 | TSHR (0.41) | ALDH1A1NPC1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL17935666 | 0.74 | ALDH1A1 (0.44) | ALDH1A1NPC1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL17935771 | 0.74 | ALDH1A1 (0.44) | ALDH1A1NPC1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL10784017 | 0.74 | ALDH1A1 (0.42) | ALDH1A1NPC1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL6021677 | 0.73 | ALDH1A1 (0.38) | ALDH1A1NPC1L3MBTL1HTTTSHR | |
| SCHEMBL8015541 | 0.73 | MCL1 (0.39) | POLB | |
| SCHEMBL2566703 | 0.72 | CASP1 (0.49) | ALDH1A1NPC1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL7643503 | 0.71 | ALDH1A1 (0.42) | ALDH1A1NPC1L3MBTL1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
| WO-2005026159-A1 | BENZOXAZOLE ACETONITRILES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | PKD1, PC, GPR119 | ALDH1A1 2797/4885NPC1 1847/4885L3MBTL1 3209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.