Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471010 | 0.83 | NR3C1 (0.49) | NR3C1TRPV1OPRM1PGRAR | |
| SCHEMBL5473124 | 0.80 | NR3C1 (0.72) | NR3C1PGR | |
| SCHEMBL5474390 | 0.77 | NR3C1 (0.31) | NR3C1 | |
| SCHEMBL5474388 | 0.77 | NR3C1 (0.31) | NR3C1 | |
| SCHEMBL5466882 | 0.77 | NR3C1 (0.56) | NR3C1 | |
| SCHEMBL5475334 | 0.77 | NR3C1 (0.38) | NR3C1TRPV1PGRAR | |
| SCHEMBL5471677 | 0.75 | NR3C1 (0.50) | NR3C1TRPV1 | |
| SCHEMBL5484786 | 0.74 | NR3C1 (0.43) | NR3C1TRPV1OPRM1 | |
| SCHEMBL5474786 | 0.67 | NR3C1 (0.34) | NR3C1 | |
| SCHEMBL5474490 | 0.67 | TRPV1 (0.37) | NR3C1TRPV1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129358-A1 | Sbstituted chroman derivatives, processes for their preparation and their use as antiinflammatory agents | SCHERING AG (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129358-A1 | Sbstituted chroman derivatives, processes for their preparation and their use as antiinflammatory agents | TNF, CXCL8, MPO | NR3C1 83/4885TRPV1 1347/4885OPRM1 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.