Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474490 | 0.82 | TRPV1 (0.37) | NR3C1PGRARTRPV1ENPP1 | |
| SCHEMBL5467716 | 0.79 | NR3C1 (0.44) | NR3C1PGRARTRPV1 | |
| SCHEMBL5482037 | 0.77 | NR3C1 (0.49) | NR3C1PGRARTRPV1 | |
| SCHEMBL5471334 | 0.77 | KDM4C (0.30) | KDM4CENPP1 | |
| SCHEMBL5471341 | 0.77 | KDM4C (0.30) | KDM4CENPP1 | |
| SCHEMBL5471338 | 0.77 | KDM4C (0.30) | KDM4CENPP1 | |
| SCHEMBL5474835 | 0.72 | KDM4C (0.39) | KDM4C | |
| SCHEMBL5470506 | 0.71 | KDM4C (0.40) | KDM4C | |
| SCHEMBL5233556 | 0.67 | KDM4C (0.39) | KDM4C | |
| SCHEMBL5471010 | 0.67 | NR3C1 (0.49) | NR3C1PGRARTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129358-A1 | Sbstituted chroman derivatives, processes for their preparation and their use as antiinflammatory agents | SCHERING AG (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129358-A1 | Sbstituted chroman derivatives, processes for their preparation and their use as antiinflammatory agents | TNF, CXCL8, MPO | NR3C1 83/4885KDM4C 3261/4885PGR 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.