SCHEMBL5482091

SCHEMBL5482091

CC(C)N(C(C)C)[PH](O)(CCC#N)OC[C@H]1O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)C[C@@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 9/20 0.37
PRMT6 Q96LA8 1/20 0.36
P2RY2 P41231 1/20 0.36
P2RY1 P47900 1/20 0.36
P2RY6 Q15077 1/20 0.36
DNPH1 O43598 1/20 0.35
DOT1L Q8TEK3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5482086 0.85 P2RY12 (0.37) P2RY12PRMT6P2RY2P2RY1P2RY6
SCHEMBL17231772 0.85 P2RY12 (0.37) P2RY12PRMT6P2RY2P2RY1P2RY6
SCHEMBL5490977 0.84 POLB (0.36) P2RY6
SCHEMBL17272943 0.83 POLB (0.49) P2RY12P2RY2P2RY6
SCHEMBL5925300 0.82 TYMP (0.39) P2RY12PRMT6
SCHEMBL8666792 0.81 P2RY12 (0.44) P2RY12PRMT6P2RY2P2RY1P2RY6
SCHEMBL7516040 0.81 P2RY12 (0.44) P2RY12PRMT6P2RY2P2RY1P2RY6
SCHEMBL19771221 0.81 P2RY12 (0.43) P2RY12PRMT6P2RY2P2RY1P2RY6
SCHEMBL19767623 0.81 P2RY12 (0.43) P2RY12PRMT6P2RY2P2RY1P2RY6
SCHEMBL17283109 0.81 P2RY12 (0.43) P2RY12PRMT6P2RY2P2RY1P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070117773-A1 Telomerase-inhibiting ENA oligonucleotide SANKYO COMPANY, LIMITED (JP) 2007-05-24 US disclosed
EP-1783216-A1 TELOMERASE-INHIBITORY ENA OLIGONUCLEOTIDE Sankyo Company, Limited (JP) 2007-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070117773-A1 Telomerase-inhibiting ENA oligonucleotide TERT, ENO1, TERB1 P2RY12 1500/4885PRMT6 2148/4885P2RY2 2572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.