Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474062 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNAHRH3 | |
| SCHEMBL3156886 | 0.78 | KDM4E (0.73) | CCR2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL1576273 | 0.77 | SIGMAR1 (0.55) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5482658 | 0.76 | KDM4E (0.47) | CCR2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL5626457 | 0.75 | ALDH1A1 (0.74) | CCR2ALDH1A1KDM4EBCHEACHE | |
| SCHEMBL2206628 | 0.75 | KDM4E (0.73) | CCR2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL3151686 | 0.75 | POLB (0.71) | CCR2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL27301766 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EBCHEACHEBACE1 | |
| SCHEMBL10425934 | 0.74 | HRH3 (0.41) | CCR2ALDH1A1ACHELMNAMAPT | |
| SCHEMBL3143167 | 0.74 | KDM4E (0.71) | CCR2ALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | MAPK1, NOS1, NOS2 | CCR2 183/4885ALDH1A1 1694/4885KDM4E 4309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.