Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790451 | 0.76 | CTSK (0.54) | MEN1KMT2ALMNACTSLCTSB | |
| SCHEMBL10658214 | 0.75 | CTSK (0.53) | MEN1KMT2ALMNACTSLCTSB | |
| SCHEMBL10487578 | 0.75 | CTSK (0.53) | MEN1KMT2ALMNACTSLCTSB | |
| SCHEMBL6726309 | 0.74 | MEN1 (0.51) | MEN1KMT2ALMNACTSLCTSB | |
| SCHEMBL6311475 | 0.73 | CTSK (0.70) | MEN1KMT2ALMNACTSLCTSB | |
| SCHEMBL5192015 | 0.73 | CTSK (0.70) | MEN1KMT2ALMNACTSLCTSB | |
| SCHEMBL6782182 | 0.73 | CTSK (0.70) | MEN1KMT2ALMNACTSLCTSB | |
| SCHEMBL10795035 | 0.73 | CTSK (0.50) | MEN1KMT2ALMNACTSLCTSB | |
| SCHEMBL79894 | 0.72 | SLC6A4 (0.47) | MEN1KMT2ALMNASLC6A2SLC6A4 | |
| SCHEMBL11130209 | 0.72 | CTSK (0.49) | MEN1KMT2ALMNACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070117803-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117803-A1 | Cyclohexyl-1,4-diamine compounds | PKD1, DDC, DPYD | MEN1 713/4885KMT2A 3604/4885LMNA 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.