Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493502 | 0.88 | FFAR1 (0.48) | FFAR1TAAR1KCNH2MMP12HIF1A | |
| SCHEMBL1599233 | 0.87 | SIGMAR1 (0.48) | HDAC2HDAC1MAOBHTR2A | |
| SCHEMBL1304308 | 0.86 | HSD11B1 (0.39) | FFAR1HSD11B1HDAC2FDFT1HDAC1 | |
| SCHEMBL17442485 | 0.85 | MAOB (0.36) | TAAR1MAOBHTR2AHIF1A | |
| SCHEMBL1203381 | 0.81 | MAOA (0.52) | KCNH2MAOBHTR2A | |
| SCHEMBL3795740 | 0.81 | HRH3 (0.35) | HSD11B1HRH3MAOBHTR2AHIF1A | |
| SCHEMBL30869989 | 0.80 | HDAC2 (0.60) | FFAR1HSD11B1HDAC2FDFT1HDAC1 | |
| SCHEMBL23584372 | 0.80 | HSD11B1 (0.38) | HSD11B1TAAR1KCNH2 | |
| SCHEMBL1316206 | 0.79 | KCNH2 (0.42) | KCNH2MAOBHTR2A | |
| SCHEMBL3688326 | 0.79 | KCNH2 (0.42) | KCNH2MAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |