Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 5/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 4/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483434 | 0.88 | FFAR1 (0.46) | FFAR1TAAR1HIF1AKCNH2MMP12 | |
| SCHEMBL2861031 | 0.87 | MAOB (0.39) | FFAR1TAAR1HIF1AKCNH2MMP12 | |
| SCHEMBL2864709 | 0.87 | FFAR1 (0.38) | FFAR1TAAR1HIF1AKCNH2MMP12 | |
| SCHEMBL208903 | 0.86 | TDP1 (0.52) | TAAR1KCNH2IDO1LMNATSHR | |
| SCHEMBL6532094 | 0.84 | TDP1 (0.50) | TAAR1KCNH2IDO1LMNATSHR | |
| SCHEMBL6848455 | 0.83 | CA2 (0.38) | TAAR1IDO1CYP1A2 | |
| SCHEMBL5486120 | 0.82 | AGXT (0.47) | HIF1AAGXTCYP11B1CYP11B2 | |
| SCHEMBL2867796 | 0.82 | TP53 (0.35) | FFAR1HIF1AHTTCYP1A2 | |
| SCHEMBL5488841 | 0.78 | FFAR1 (0.53) | FFAR1TSHR | |
| SCHEMBL5494552 | 0.77 | TAAR1 (0.50) | FFAR1TAAR1IDO1AGXTABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |