Glycitein

Glycitein

SCHEMBL8065644

COc1cc2c(=O)c(-c3ccc(O)cc3)coc2cc1O.O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12.O=c1c(-c2ccc(O)cc2)coc2cc(O)ccc12

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 4/20 0.78
RAB9A P51151 8/20 0.68
KDM4E B2RXH2 7/20 0.68
MAPT P10636 7/20 0.68
NPC1 O15118 6/20 0.68
POLB P06746 3/20 0.68
HMGB1 P09429 1/20 0.68
KLK7 P49862 1/20 0.66
SMN1; SMN2 Q16637 7/20 0.65
TP53 P04637 6/20 0.65
ALDH1A1 P00352 6/20 0.65
CYP3A4 P08684 6/20 0.65
HPGD P15428 6/20 0.65
CYP2C9 P11712 5/20 0.65
CYP2C19 P33261 5/20 0.65
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
MAOA P21397 4/20 0.65
MAOB P27338 4/20 0.65
ALOX15 P16050 4/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycitein SCHEMBL3928329 0.97 HDAC6 (0.83) HDAC6RAB9AKDM4EMAPTNPC1
Glycitein SCHEMBL5483545 0.93 HDAC6 (0.91) HDAC6RAB9AKDM4EMAPTNPC1
Formononetin SCHEMBL6312014 0.89 MAPT (0.83) HDAC6RAB9AKDM4EMAPTNPC1
Formononetin SCHEMBL4223418 0.89 MAPT (0.83) HDAC6RAB9AKDM4EMAPTNPC1
Glycitein SCHEMBL6578666 0.89 RAB9A (0.85) HDAC6RAB9AKDM4EMAPTNPC1
Glycitein SCHEMBL29497281 0.88 HDAC6 (1.00) HDAC6RAB9AKDM4EMAPTNPC1
Glycitein SCHEMBL7733712 0.88 HDAC6 (1.00) HDAC6RAB9AKDM4EMAPTNPC1
Genistein SCHEMBL5801778 0.88 SMN1; SMN2 (0.84) HDAC6RAB9AKDM4EMAPTNPC1
Glycitein SCHEMBL19720 0.88 HDAC6 (1.00) HDAC6RAB9AKDM4EMAPTNPC1
Glycitein SCHEMBL360612 0.85 HDAC6 (0.56) HDAC6RAB9AKDM4EMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6146669-A BIOLOGICAL MODIFICATION OF AN OIL SEED MATERIAL BY INCUBATING CULTURE OF OIL SEED MATERIAL AND MICROORGANISMS IN THE PRESENCE OF OXYGEN TO PRODUCE OIL SEED MATERIAL HAVING A HIGHER PROTEIN CONTENT THAN BEFORE INCUBATING; USE IN FEEDS CARGILL INCORPORATED (US) 2000-11-14 US disclosed
US-5919921-A CONDENSING SOY MOLASSES TO AT LEAST 10% SOLIDS BY WEIGHT, MAINTAINING PRODUCT AT PH AND TEMPERATURE MAKING ISOFLAVONES INSOLUBLE, SEPARATING INSOLUBLE PRODUCT FROM LIQUID PROTEIN TECHNOLOGIES INTERNATIONAL, INC. (US) 1999-07-06 US disclosed
EP-0906029-A1 NOVEL ISOFLAVONE-ENRICHED SOY PROTEIN PRODUCT AND METHOD FOR ITS MANUFACTURE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-07 EP disclosed
US-5858449-A INGREDIENT IN THE PRODUCTION OF DAIRY OR MEAT BASED FOOD PRODUCTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-12 US disclosed
WO-1997037547-A1 NOVEL ISOFLAVONE-ENRICHED SOY PROTEIN PRODUCT AND METHOD FOR ITS MANUFACTURE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-10-16 WO disclosed