Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928340 | 0.84 | THRB (0.35) | CYP2C19ATMTDP1THRBMEN1 | |
| SCHEMBL4070526 | 0.78 | CYP2C19 (0.37) | CYP2C19ATMTDP1THRBMEN1 | |
| SCHEMBL28147925 | 0.77 | KMT2A (0.38) | CYP2C19THRBMEN1KMT2AACHE | |
| SCHEMBL31132053 | 0.76 | THRB (0.39) | CYP2C19ATMTDP1THRBNPSR1 | |
| SCHEMBL28285845 | 0.75 | THRB (0.35) | CYP2C19THRBMEN1KMT2AACHE | |
| Acrylamide SCHEMBL28928535 | 0.74 | ALDH1A1 (0.37) | CYP2C19ATMTDP1MEN1KMT2A | |
| SCHEMBL19719090 | 0.73 | ACHE (0.33) | THRBACHEALDH1A1TSHR | |
| SCHEMBL30887689 | 0.71 | CYP2C19 (0.44) | CYP2C19THRBKMT2AGAASMN1; SMN2 | |
| SCHEMBL27736690 | 0.71 | NPC1 (0.42) | TDP1NPSR1GAASMN1; SMN2MAPT | |
| SCHEMBL29577536 | 0.71 | THRB (0.43) | TDP1THRBMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071475-A1 | Method For Producing An Oral Pharmaceutical Form With Immediate Disintegration And Active Ingredient Release | ROEHM GMBH (DE) | 2013-03-21 | — | — | US | disclosed |
| US-8343542-B2 | Method for producing an immediately decomposing oral form of administration which releases active ingredients | EVONIK ROEHM GMBH (DE) | 2013-01-01 | — | — | US | disclosed |
| US-7160558-B2 | Coating and binding agent for pharmaceutical formulations with improved storage stability | ROEHM GMBH & CO. KG (DE) | 2007-01-09 | — | — | US | disclosed |
| US-20060051412-A1 | Method for producing an immediately decomposing oral form of administration which releases active ingredients | ROEHM GMBH & CO. KG (DE) | 2006-03-09 | — | — | US | disclosed |
| US-20050142174-A1 | Adhesive and binding agent for dermal or transdermal treatment systems | ROEHM GMBH & CO. KG | 2005-06-30 | — | — | US | disclosed |