SCHEMBL27736690

SCHEMBL27736690

C=CC(=O)OC(C)(C)Nc1ccccc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
HPGD P15428 3/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 3/20 0.40
PDK1 Q15118 1/20 0.40
PDK2 Q15119 1/20 0.40
PDK3 Q15120 1/20 0.40
PDK4 Q16654 1/20 0.40
KDM4E B2RXH2 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
DHODH Q02127 1/20 0.38
POLB P06746 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
EGFR P00533 1/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4928340 0.73 THRB (0.35) ALDH1A1GAATDP1SMN1; SMN2
O-Xylene SCHEMBL27798322 0.71 ALDH1A1 (0.42) NPC1RAB9AHPGDALDH1A1GAA
SCHEMBL5483835 0.71 CYP2C19 (0.35) RAB9AHPGDALDH1A1GAATDP1
Toluene SCHEMBL3759688 0.69 THRB (0.40) ALDH1A1TDP1MAPTALOX12
SCHEMBL29223274 0.69 NPC1 (0.48) NPC1RAB9AHPGDALDH1A1GAA
SCHEMBL648951 0.68 NPC1 (0.62) NPC1RAB9AHPGDALDH1A1GAA
SCHEMBL31132053 0.68 THRB (0.39) ALDH1A1TDP1POLBNPSR1
SCHEMBL4406254 0.68 RAB9A (0.52) NPC1RAB9AHPGDALDH1A1GAA
SCHEMBL3169549 0.68 CYP2C19 (0.46) ALDH1A1GAAKDM4ESMN1; SMN2MAPT
Acrylic Acid Methyl Ester SCHEMBL27522901 0.68 ALDH1A1 (0.42) NPC1RAB9AHPGDALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101348536-B Emulsion polymer comprising activators, process for preparation thereof and use thereof in two-component or multicomponent systems EVONIK ROEHM GMBH 2014-06-11 CN disclosed
CN-101343335-A Two or more-component system cured by a redox initiator system with controllable working life, and the use thereof EVONIK ROEHM GMBH (DE) 2009-01-14 CN disclosed