Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 4/20 | 0.46 |
| ▸ | BRAF | P15056 | 7/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14292730 | 0.86 | TEK (0.45) | TEKBRAFNR1H4TRPV1HDAC3 | |
| SCHEMBL4727348 | 0.86 | TEK (0.45) | TEKBRAFNR1H4TRPV1HDAC3 | |
| SCHEMBL4414872 | 0.84 | BRAF (0.49) | TEKBRAFCYP2C9NR1H4NR1I2 | |
| SCHEMBL4725070 | 0.84 | TEK (0.46) | TEKBRAFTRPV1 | |
| SCHEMBL5498870 | 0.83 | TAS2R14 (0.46) | TEKBRAFNR1H4NR1I2 | |
| SCHEMBL4410252 | 0.82 | BRAF (0.46) | TEKBRAFCYP2C9 | |
| SCHEMBL5482540 | 0.82 | RAB9A (0.48) | TEKBRAF | |
| SCHEMBL4725698 | 0.81 | RAF1 (0.48) | TEKBRAFNR1H4 | |
| SCHEMBL4411284 | 0.81 | KCNQ3 (0.46) | TEKBRAFCYP2C9 | |
| SCHEMBL5488046 | 0.80 | BRAF (0.44) | TEKBRAFCYP2C9NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |