Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 14/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14534446 | 0.94 | BRAF (0.43) | BRAFCYP2C9TEKHCAR3HCAR2 | |
| SCHEMBL4410252 | 0.89 | BRAF (0.46) | BRAFCYP2C9TEK | |
| SCHEMBL14534457 | 0.88 | BRAF (0.43) | BRAFCYP2C9HCAR3HCAR2AURKA | |
| SCHEMBL14534685 | 0.87 | BRAF (0.41) | BRAFCYP2C9HCAR3HCAR2AURKA | |
| SCHEMBL4415237 | 0.87 | CRHR1 (0.44) | BRAFCYP2C9TEK | |
| SCHEMBL4411284 | 0.85 | KCNQ3 (0.46) | BRAFCYP2C9TEK | |
| SCHEMBL4410203 | 0.82 | HCAR3 (0.44) | BRAFCYP2C9TEKHCAR3 | |
| SCHEMBL4414329 | 0.81 | BRAF (0.43) | BRAFCYP2C9TEK | |
| SCHEMBL4414872 | 0.81 | BRAF (0.49) | BRAFCYP2C9TEKNR1H4 | |
| SCHEMBL5483879 | 0.80 | TEK (0.46) | BRAFCYP2C9TEKNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |