SCHEMBL548393

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7154020	0.83	CYP1A2 (0.39)	CYP1A2ERN1ALDH1A1ALOX15SELL
	SCHEMBL547555	0.81	ALDH1A1 (0.46)	ERN1ALDH1A1ALOX15TSHRCA12
	SCHEMBL30827005	0.81	ERN1 (0.34)	ERN1ALDH1A1ALOX15TYRTDP1
	SCHEMBL547605	0.78	CYP3A4 (0.35)	CYP1A2ERN1ALDH1A1ALOX15TDP1
	SCHEMBL17740051	0.78	SELL (0.50)	CYP1A2ERN1ALDH1A1ALOX15SELL
	SCHEMBL548457	0.78	TDP1 (0.50)	ERN1ALDH1A1TSHRTYRTDP1
	SCHEMBL10050030	0.77	CYP1A2 (0.59)	CYP1A2ERN1ALDH1A1ALOX15SELL
	SCHEMBL548167	0.77	ERN1 (0.42)	CYP1A2ERN1ALDH1A1ALOX15POLB
	SCHEMBL7537564	0.76	CYP1A2 (0.44)	CYP1A2ERN1ALDH1A1ALOX15SELL
	Benzene SCHEMBL28172839	0.75	ALDH1A1 (0.55)	ALDH1A1ALOX15TSHRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.