SCHEMBL30827005

SCHEMBL30827005

O=Cc1ccc(C(=O)Cl)c(C=O)c1C=O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.34
TDP1 Q9NUW8 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TYR P14679 1/20 0.33
ALOX15 P16050 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548393 0.81 CYP1A2 (0.42) ERN1TDP1ALDH1A1TYRALOX15
SCHEMBL548457 0.76 TDP1 (0.50) ERN1TDP1ALDH1A1TYRMEN1
Water SCHEMBL28332432 0.74 ALDH1A1 (0.45) ERN1TDP1ALDH1A1ALOX15MEN1
SCHEMBL23528851 0.72 ALDH1A1 (0.39) ERN1TDP1ALDH1A1ALOX15MEN1
SCHEMBL7536432 0.70 LMNA (0.52) ERN1TDP1ALDH1A1ALOX15MEN1
SCHEMBL29951511 0.70 LMNA (0.52) ERN1TDP1ALDH1A1ALOX15MEN1
SCHEMBL7154020 0.69 CYP1A2 (0.39) ERN1TDP1ALDH1A1ALOX15
SCHEMBL7539950 0.69 ERN1 (0.36) ERN1TDP1ALDH1A1TYRALOX15
SCHEMBL3451683 0.69 ERN1 (0.50) ERN1TYRMEN1KMT2ATRIM24
SCHEMBL13208560 0.68 SRC (0.50) ERN1TDP1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112094296-B Preparation method of bis (2, 4, 6-trimethylbenzoyl) phenylphosphine oxide 山东久日化学科技有限公司 2024-03-29 CN claimed