Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19717824 | 0.85 | ALDH1A1 (0.55) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL10789091 | 0.84 | NPC1 (0.68) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL7811547 | 0.84 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL21747466 | 0.84 | ALDH1A1 (0.52) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL8544763 | 0.84 | ALDH1A1 (0.55) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL5319254 | 0.82 | HTR1A (0.48) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL14435818 | 0.81 | ALDH1A1 (0.51) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL3359449 | 0.79 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL7598113 | 0.79 | HTR1A (0.55) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL5594953 | 0.79 | MAOB (0.55) | HTR1AADRA1DADRA1AADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |