Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697908 | 0.81 | OPRM1 (0.87) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL5483991 | 0.80 | OPRM1 (0.54) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL4755802 | 0.77 | OPRM1 (0.50) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL4698127 | 0.74 | OPRM1 (1.00) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL4697915 | 0.73 | OPRM1 (0.64) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL4697868 | 0.72 | OPRM1 (0.77) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL4698672 | 0.69 | OPRM1 (0.85) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL4698114 | 0.69 | OPRM1 (0.88) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL5852064 | 0.68 | OPRM1 (0.57) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL5407371 | 0.68 | OPRM1 (0.52) | OPRM1OPRD1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054950-A1 | 3-Azabicyclo[3.1.0]hexane derivatives | PFIZER INC. | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054950-A1 | 3-Azabicyclo[3.1.0]hexane derivatives | OPRD1, OPRM1, OPRK1 | OPRM1 2/4885OPRD1 1/4885OPRK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.