SCHEMBL5484066

SCHEMBL5484066

CCN(CC)CC(=O)OC1=CC(=O)C=C2CC[C@@H]3[C@H]([C@@H](O)C[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO)[C@]21C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 12/20 0.60
NR3C1 P04150 6/20 0.60
HSD17B10 Q99714 5/20 0.60
PGR P06401 5/20 0.60
CYP3A4 P08684 5/20 0.60
CYP2C19 P33261 3/20 0.60
SERPINA6 P08185 3/20 0.60
NR3C2 P08235 3/20 0.60
AR P10275 2/20 0.60
ABCB11 O95342 2/20 0.60
TNF P01375 1/20 0.60
IL6 P05231 1/20 0.60
GLUL P15104 1/20 0.60
ADAM17 P78536 1/20 0.60
GPBAR1 Q8TDU6 1/20 0.60
SMN1; SMN2 Q16637 3/20 0.56
KMT2A Q03164 2/20 0.56
MAPT P10636 2/20 0.56
SHBG P04278 1/20 0.56
NFKB1 P19838 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21332954 1.00 HIF1A (0.60) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL35449 0.91 HIF1A (0.64) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL27781029 0.91 HIF1A (0.66) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL945988 0.90 HIF1A (0.65) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL11068491 0.90 HIF1A (0.62) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL264554 0.90 HIF1A (0.64) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL677626 0.89 HIF1A (0.61) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL2326922 0.89 HIF1A (0.63) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL28480766 0.89 HIF1A (0.67) HIF1ANR3C1HSD17B10PGRCYP3A4
SCHEMBL5955148 0.88 HIF1A (0.62) HIF1ANR3C1HSD17B10PGRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107427584-A Joint fat pad preparation and its application method 阿勒根公司 2017-12-01 CN claimed
CN-101060831-A Conveniently implantable sustained release pharmaceutical composition RAMSCOR INC (US) 2007-10-24 CN claimed
EP-1829527-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-09-05 EP claimed
EP-1829528-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-09-05 EP claimed
EP-1815846-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-08-08 EP claimed
EP-1815847-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-08-08 EP claimed
CN-1703199-A Aggregate with enhanced deformability comprising at least three amphiphiles for improved transport through a semi-permeable barrier and use of non-invasive drugs in vivo, in particular through the skin IDEA AG (DE) 2005-11-30 CN claimed
EP-1551370-A1 AGGREGATE WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN IDEA AG (DE) 2005-07-13 EP claimed
US-20040105881-A1 Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2004-06-03 US claimed
WO-2004032900-A1 AGGREGATE WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN IDEA AG (DE) 2004-04-22 WO claimed
CN-118355029-A Methods of treating diffuse large B-cell lymphomas using anti-CD 79B immunoconjugates 基因泰克公司 2024-07-16 CN disclosed
EP-4380978-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA Genentech, Inc. (US) 2024-06-12 EP disclosed
US-20230099756-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA GENENTECH, INC. (US) 2023-03-30 US disclosed
WO-2023019092-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA GENENTECH, INC. (US) 2023-02-16 WO disclosed
CN-107427584-A Joint fat pad preparation and its application method 阿勒根公司 2017-12-01 CN disclosed
CN-104334196-A Histidyl-trna synthetases for treating autoimmune and inflammatory diseases ATYR PHARMA INC 2015-02-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230099756-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA CD79B, CD99, BCL6 HIF1A 4135/4885NR3C1 624/4885HSD17B10 2069/4885
US-20040105881-A1 Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin CUTA, ABCG2, PIGS HIF1A 3394/4885NR3C1 1903/4885HSD17B10 3257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.