SCHEMBL5484080

SCHEMBL5484080

Cc1ccc(C[Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
AGXT P21549 2/20 0.41
CYP11B1 P15538 2/20 0.41
CYP11B2 P19099 2/20 0.41
CYP19A1 P11511 1/20 0.41
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.36
ESR1 P03372 1/20 0.36
CHRM2 P08172 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4450244 0.86 ESR1 (0.38) IDO1ESR1
SCHEMBL31366860 0.82 IDO1 (0.44) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL2687231 0.78 HRH3 (0.41) CYP2A6TAAR1CYP11B1CYP11B2CYP19A1
SCHEMBL1479279 0.76 IDO1 (0.48) IDO1CYP2A6TAAR1AGXTCYP11B1
SCHEMBL7557619 0.76 CA1 (0.39) ESR1
SCHEMBL986310 0.76 ESR1 (0.61) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL7333275 0.75 IDO1 (0.42) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL840528 0.75 CYP1A2 (0.50) IDO1CYP1A2CYP2A6TAAR1ACHE
SCHEMBL20473031 0.75 TSHR (0.44) CYP1A2ACHETP53MAPTLMNA
SCHEMBL2684489 0.74 IDO1 (0.46) IDO1TAAR1AGXTCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME JSI SILICONE CO. (KR) 2021-06-24 US disclosed
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME PFAS, FRK, AGPAT2 IDO1 2819/4885CYP1A2 303/4885CYP2A6 121/4885
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 IDO1 2819/4885CYP1A2 303/4885CYP2A6 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.