Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450244 | 0.86 | ESR1 (0.38) | IDO1 | |
| SCHEMBL2785168 | 0.80 | IDO1 (0.42) | IDO1LOXL2TAAR1AGXTCYP19A1 | |
| SCHEMBL2687231 | 0.78 | HRH3 (0.41) | TAAR1CYP19A1CYP11B1CYP11B2MAOB | |
| SCHEMBL1479279 | 0.76 | IDO1 (0.48) | IDO1TAAR1AGXTCYP19A1CYP11B1 | |
| SCHEMBL7557619 | 0.76 | CA1 (0.39) | — | |
| SCHEMBL5552238 | 0.74 | ESR1 (0.31) | — | |
| SCHEMBL5484080 | 0.74 | IDO1 (0.46) | IDO1TAAR1AGXTCYP19A1CYP11B1 | |
| SCHEMBL15734925 | 0.74 | IDO1 (0.46) | IDO1LOXL2TAAR1AGXTPLA2G1B | |
| SCHEMBL19064379 | 0.74 | ESR1 (0.58) | IDO1LOXL2TAAR1AGXTLMNA | |
| SCHEMBL5485087 | 0.74 | TAAR1 (0.42) | IDO1TAAR1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102498117-A | Organic Chlorosilane And Method For Preparing Same | SAMSUNG FINE CHEMICALS CO LTD | 2012-06-13 | — | — | CN | disclosed |
| US-20120114544-A1 | ORGANIC CHLOROHYDROSILANE AND METHOD FOR PREPARING THEM | SAMSUNG FINE CHEMICALS CO., LTD (KR) | 2012-05-10 | — | — | US | disclosed |
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-20020082438-A1 | PROCESS FOR PREPARING ORGANOCHLOROSILANES BY DEHYDROHALOGENATIVE COUPLING REACTION OF ALKYL HALIDES WITH CHLOROSILANES | JUNG IL-NAM (KR) | 2002-06-27 | — | — | US | disclosed |
| US-6392077-B1 | DEHYDROHALOGENATION | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-05-21 | — | — | US | disclosed |
| US-6251057-B1 | FORMING SILICON-CARBON BONDS FOR USE IN ORGANOSILICON COMPOUNDS SYNTHESIS; ACTIVATED ALKYL HALIDES AND UNACTIVATED ALKYL HALIDES | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2001-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114544-A1 | ORGANIC CHLOROHYDROSILANE AND METHOD FOR PREPARING THEM | PHPT1, SIK1, SIK2 | IDO1 4715/4885LOXL2 3021/4885TAAR1 4222/4885 |
| US-20020082438-A1 | PROCESS FOR PREPARING ORGANOCHLOROSILANES BY DEHYDROHALOGENATIVE COUPLING REACTION OF ALKYL HALIDES WITH CHLOROSILANES | RCC1, RER1, RIF1 | IDO1 3000/4885LOXL2 2011/4885TAAR1 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.