SCHEMBL4450244

SCHEMBL4450244

Cl[Si](Cl)(Cl)Cc1ccc(C[Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.38
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2687231 0.91 HRH3 (0.41) ESR1
SCHEMBL1479279 0.88 IDO1 (0.48) IDO1
SCHEMBL7557619 0.88 CA1 (0.39) ESR1
SCHEMBL5485087 0.86 TAAR1 (0.42) IDO1
SCHEMBL2684489 0.86 IDO1 (0.46) IDO1
SCHEMBL5552238 0.86 ESR1 (0.31) ESR1
SCHEMBL242725 0.84 CALM1 (0.45) IDO1
SCHEMBL5494552 0.82 TAAR1 (0.50) IDO1
SCHEMBL9715824 0.80 ALDH1A1 (0.50)
SCHEMBL297636 0.80 IDO1 (0.52) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343638-A Porous spin-on dielectric coating materials from silicon-containing polymers 上海艾深斯科技有限公司 2024-01-05 CN claimed
US-9399720-B2 High gain durable anti-reflective coating Enki Technology, Inc. (US) 2016-07-26 US claimed
US-20160032147-A1 HIGH GAIN DURABLE ANTI-REFLECTIVE COATING JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2016-02-04 US claimed
US-12168705-B2 Modified high cis polydiene polymer, related methods and rubber compositions BRIDGESTONE CORPORATION (JP) 2024-12-17 US disclosed
EP-3938412-B1 MODIFIED HIGH CIS POLYDIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE CORP (JP) 2024-04-24 EP disclosed
CN-117343638-A Porous spin-on dielectric coating materials from silicon-containing polymers 上海艾深斯科技有限公司 2024-01-05 CN disclosed
CN-108349748-B Polyoxometallates comprising noble metals and corresponding metal clusters 埃克森美孚化学专利公司 2022-11-04 CN disclosed
US-11452993-B2 Polyoxometalates comprising noble metals and corresponding metal clusters EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-09-27 US disclosed
CN-110446550-B Polyoxometallates comprising noble and late transition metals and metal clusters thereof 埃克森美孚化学专利公司 2022-07-19 CN disclosed
US-20220185931-A1 Modified High Cis Polydiene Polymer, Related Methods And Rubber Compositions BRIDGESTONE CORPORATION (JP) 2022-06-16 US disclosed
US-11241677-B2 Polyoxometalates comprising noble metals and post-transition metals and metal clusters thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-02-08 US disclosed
US-9399720-B2 High gain durable anti-reflective coating Enki Technology, Inc. (US) 2016-07-26 US disclosed
US-9376589-B2 High gain durable anti-reflective coating with oblate voids Enki Technology, Inc. (US) 2016-06-28 US disclosed
US-20160032141-A1 HIGH GAIN DURABLE ANTI-REFLECTIVE COATING JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2016-02-04 US disclosed
US-20160032147-A1 HIGH GAIN DURABLE ANTI-REFLECTIVE COATING JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2016-02-04 US disclosed
US-8080493-B2 Heteropolyanions with late transition metal addenda atoms and process for their preparation EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-12-20 US disclosed
US-20090216052-A1 Novel Heteropolyanions With Late Transition Metal Addenda Atoms And Process For Their Preparation EXXONMOBIL CHEMICAL PATENTS INC. 2009-08-27 US disclosed
US-20020082438-A1 PROCESS FOR PREPARING ORGANOCHLOROSILANES BY DEHYDROHALOGENATIVE COUPLING REACTION OF ALKYL HALIDES WITH CHLOROSILANES JUNG IL-NAM (KR) 2002-06-27 US disclosed
US-6392077-B1 DEHYDROHALOGENATION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2002-05-21 US disclosed
US-6251057-B1 FORMING SILICON-CARBON BONDS FOR USE IN ORGANOSILICON COMPOUNDS SYNTHESIS; ACTIVATED ALKYL HALIDES AND UNACTIVATED ALKYL HALIDES KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2001-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020082438-A1 PROCESS FOR PREPARING ORGANOCHLOROSILANES BY DEHYDROHALOGENATIVE COUPLING REACTION OF ALKYL HALIDES WITH CHLOROSILANES RCC1, RER1, RIF1 ESR1 2585/4885IDO1 3000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.