Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484250 | 0.88 | TSHR (0.44) | TSHRTDP1ALDH1A1MAPTALOX15 | |
| SCHEMBL6057969 | 0.86 | TSHR (0.43) | TSHRTDP1ALDH1A1MAPTALOX15 | |
| SCHEMBL3393735 | 0.84 | GPR35 (0.46) | TSHRTDP1ALDH1A1MAPTALOX15 | |
| SCHEMBL28146285 | 0.82 | TSHR (0.44) | TSHRTDP1ALDH1A1MAPTALOX15 | |
| SCHEMBL1933923 | 0.80 | TSHR (0.47) | TSHRTDP1ALDH1A1MAPTALOX15 | |
| SCHEMBL10586114 | 0.78 | TDP1 (0.40) | TSHRTDP1ALDH1A1MAPTALOX15 | |
| SCHEMBL460054 | 0.78 | TDP1 (0.38) | TSHRTDP1ALDH1A1MAPTALOX15 | |
| SCHEMBL7159890 | 0.77 | GPR35 (0.54) | TSHRTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL16863642 | 0.76 | TSHR (0.40) | TSHRTDP1ALDH1A1MAPTALOX15 | |
| SCHEMBL13726953 | 0.76 | TSHR (0.43) | TSHRTDP1ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266651-A | Crosslinked poled polymers for nonlinear optic applications and method of making them | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-30 | — | — | US | claimed |
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |