SCHEMBL5484252

SCHEMBL5484252

O=C(O)c1ccc(CN2C(=O)C=CC2=O)cc1N1C(=O)CCC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
MGLL Q99685 4/20 0.45
FAAH O00519 2/20 0.45
HDAC7 Q8WUI4 1/20 0.43
GSK3A P49840 2/20 0.41
GSK3B P49841 2/20 0.41
MYC P01106 1/20 0.37
MAPK1 P28482 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
GAA P10253 2/20 0.35
ALDH1A1 P00352 2/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 2/20 0.35
HDAC1 Q13547 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9596295 0.80 CA12 (0.39) HDAC7MYCMAPK1CA12CA1
SCHEMBL6887707 0.73 CA12 (0.48) PTGS2MYCMAPK1CA12CA1
SCHEMBL31672304 0.73 MYC (0.34) HDAC7MYCKMT2AMEN1
SCHEMBL317626 0.72 CA12 (0.42) MYCMAPK1CA12CA1CA9
SCHEMBL317703 0.72 KEAP1 (0.43) MAPK1CA12CA1CA9GAA
SCHEMBL31653832 0.72 KEAP1 (0.43) MAPK1CA12CA1CA9GAA
SCHEMBL1464604 0.71 CA12 (0.41) MYCMAPK1CA12CA1CA9
SCHEMBL610788 0.71 CA12 (0.41) PTGS2MYCMAPK1CA12CA1
SCHEMBL10627311 0.70 MCL1 (0.42) MYCMAPK1CA12CA1CA9
SCHEMBL567033 0.69 KDM4E (0.38) MAPK1CA12CA1CA9GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148702-A1 MEASURING CHIP FOR SURFACE PLASMON RESONANCE BIOSENSOR AND METHOD FOR PRODUCING THE SAME Karube, Isao (JP) 2007-06-28 US claimed
US-20030224441-A1 Measuring chip for surface plasmon resonance biosensor and method for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2003-12-04 US claimed
US-6627397-B1 Comprising thin gold film, plasma polymerization layers, immobilized biologically active substances; use for detection of small amount of target substances in high sensitivity DAI NIPPON PRINTING CO., LTD. (JP) 2003-09-30 US claimed
US-10309888-B2 Biosensor comprising electrode for measuring hematocrit value ARKRAY, INC. (JP) 2019-06-04 US disclosed
EP-3156788-B1 BIOSENSOR ARKRAY INC (JP) 2018-12-26 EP disclosed
US-9952197-B2 Biosensor comprising electrode for measuring hematocrit value ARKRAY, INC. (JP) 2018-04-24 US disclosed
EP-3078965-B1 BIOSENSOR COMPRISING ELECTRODE FOR MEASURING HEMATOCRIT VALUE ARKRAY INC (JP) 2018-04-04 EP disclosed
EP-3086113-B1 BIOSENSOR COMPRISING ELECTRODE FOR MEASURING HEMATOCRIT VALUE ARKRAY INC (JP) 2018-01-17 EP disclosed
US-20170108458-A1 Biosensor ARKRAY, INC. (JP) 2017-04-20 US disclosed
EP-3156788-A1 BIOSENSOR ARKRAY, Inc. (JP) 2017-04-19 EP disclosed
EP-3086113-A1 BIOSENSOR COMPRISING ELECTRODE FOR MEASURING HEMATOCRIT VALUE ARKRAY, Inc. (JP) 2016-10-26 EP disclosed
US-20160290987-A1 Biosensor Comprising Electrode for Measuring Hematocrit Value ARKRAY, INC. (JP) 2016-10-06 US disclosed
US-20160290910-A1 Biosensor Comprising Electrode for Measuring Hematocrit Value ARKRAY, INC. (JP) 2016-10-06 US disclosed
US-20160186230-A1 Enzyme Electrode ARKRAY, INC. (JP) 2016-06-30 US disclosed
EP-3037812-A1 ENZYME ELECTRODE ARKRAY, Inc. (JP) 2016-06-29 EP disclosed
US-20070148702-A1 MEASURING CHIP FOR SURFACE PLASMON RESONANCE BIOSENSOR AND METHOD FOR PRODUCING THE SAME Karube, Isao (JP) 2007-06-28 US disclosed
EP-0945721-B1 Biosensitive element for surface plasmon resonance measurements, and its method of manufacture DAINIPPON PRINTING CO LTD (JP) 2004-11-17 EP disclosed
US-20030224441-A1 Measuring chip for surface plasmon resonance biosensor and method for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2003-12-04 US disclosed
US-6627397-B1 Comprising thin gold film, plasma polymerization layers, immobilized biologically active substances; use for detection of small amount of target substances in high sensitivity DAI NIPPON PRINTING CO., LTD. (JP) 2003-09-30 US disclosed
EP-0945721-A2 Biosensitive element for surface plasmon resonance measurements, and its method of manufacture DAI NIPPON PRINTING CO., LTD. (JP) 1999-09-29 EP disclosed