Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RBP4 | P02753 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473636 | 0.87 | MAPT (0.51) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL5464801 | 0.85 | MAPT (0.68) | MAPTSMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL5458584 | 0.85 | MAPT (0.53) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL5455945 | 0.85 | MAPT (0.57) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL5455975 | 0.84 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL5450980 | 0.84 | HTR1A (0.55) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL5456010 | 0.83 | MAPT (0.51) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL5462082 | 0.83 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL5453431 | 0.83 | RBP4 (0.54) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL5465476 | 0.83 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | MAPT 758/4885SMN1; SMN2 4424/4885ALDH1A1 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.