Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | L1CAM | P32004 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548547 | 0.82 | CA1 (0.47) | CA1CA9KDM4EMAPTGAA | |
| SCHEMBL3038293 | 0.77 | LMNA (0.43) | CA1CA9KDM4EMAPTGAA | |
| SCHEMBL11328037 | 0.76 | KDM4E (0.47) | CA1CA9KDM4EMAPTGAA | |
| SCHEMBL28582275 | 0.74 | KDM4E (0.57) | CA1CA9KDM4EMAPTGAA | |
| SCHEMBL29966079 | 0.73 | KDM4E (0.45) | CA1CA9KDM4EMAPTGAA | |
| SCHEMBL78143 | 0.73 | KDM4E (0.45) | CA1CA9KDM4EMAPTGAA | |
| SCHEMBL5685341 | 0.72 | NAAA (0.50) | KDM4EMAPTGAASMN1; SMN2NAAA | |
| SCHEMBL28537325 | 0.72 | TSHR (0.41) | KDM4EMAPTGAASMN1; SMN2MPO | |
| SCHEMBL11689088 | 0.72 | GAA (0.41) | CA1CA9KDM4EMAPTGAA | |
| SCHEMBL15538027 | 0.72 | KDM4E (0.59) | CA1CA9KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516827-A | MIXED WITH TIN ALCOHOLATE OR CARBOXYLATE, ZINC PHENOXIDE OR CARBOXYLATE, AND THIOPHOSPHATE OR THIOPHOSPHITE | CIBA-GEIGY CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |