Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | SMO | Q99835 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645468 | 0.88 | RAB9A (0.65) | RAB9AKMT2ACYP3A4ROCK2ROCK1 | |
| SCHEMBL19380041 | 0.84 | TSHR (0.59) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL12310174 | 0.79 | KMT2A (0.76) | RAB9AKMT2ACYP3A4ROCK2ROCK1 | |
| SCHEMBL11617534 | 0.78 | RAB9A (0.75) | RAB9AKMT2ACYP3A4ROCK2ROCK1 | |
| SCHEMBL1193236 | 0.78 | PARP10 (0.59) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL11195433 | 0.77 | KMT2A (0.80) | RAB9AKMT2ACYP3A4ROCK2ROCK1 | |
| SCHEMBL31530270 | 0.77 | RAB9A (0.74) | RAB9AKMT2ACYP3A4ROCK2ROCK1 | |
| SCHEMBL9719865 | 0.76 | MEN1 (0.62) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9719803 | 0.76 | RNF4 (0.57) | RAB9ACYP3A4NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5384036 | 0.76 | ROCK2 (0.76) | RAB9AKMT2ACYP3A4ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |