SCHEMBL5485813

SCHEMBL5485813

CN(C)c1ccccc1/N=N/c1ccccc1S(=O)(=O)O.[NaH]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.44
CA2 P00918 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA4 P22748 1/20 0.41
CA9 Q16790 1/20 0.41
SUMO2 P61956 3/20 0.40
SUMO1 P63165 3/20 0.40
SENP7 Q9BQF6 3/20 0.40
SENP2 Q9HC62 3/20 0.40
SENP1 Q9P0U3 2/20 0.40
SENP3 Q9H4L4 1/20 0.40
F2 P00734 3/20 0.39
PRSS1 P07477 3/20 0.39
PRSS2 P07478 3/20 0.39
PRSS3 P35030 3/20 0.39
CYP1A2 P05177 2/20 0.39
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15136283 0.98 HTR6 (0.45) HTR6CA2CA12CA1CA4
SCHEMBL15136285 0.98 HTR6 (0.45) HTR6CA2CA12CA1CA4
SCHEMBL5485815 0.97 HTR6 (0.47) HTR6CA2CA12CA1CA4
SCHEMBL3790419 0.82 CYP1A2 (0.50) SUMO2SUMO1SENP7SENP2SENP1
SCHEMBL28584350 0.82 CA2 (0.54) HTR6CA2CA12CA1CA4
SCHEMBL28326313 0.81 HTR6 (0.58) HTR6CA2CA12CA1CA4
SCHEMBL9788043 0.80 POLB (0.58) CA2CA12CA9SUMO2SUMO1
SCHEMBL6265807 0.79 HTR6 (0.60) HTR6CA2CA12CA1CA4
SCHEMBL8722208 0.78 MAPT (0.48) HTR6CA2CA12CA1CA4
SCHEMBL333388 0.78 MYC (0.58) CA2CA12CA9SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7294370-B2 Polarizing and optical compensating films for visible, ultraviolet and infrared parts of the electromagnetic spectrum KENT STATE UNIVERSITY (US) 2007-11-13 US disclosed