Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489951 | 0.91 | TAS1R3 (0.36) | TAS1R3TAS1R1SLC6A2SLC6A4ACACB | |
| SCHEMBL5341776 | 0.87 | MMP1 (0.40) | MMP2MMP1MMP8TAS1R3TAS1R1 | |
| SCHEMBL5379472 | 0.84 | MMP1 (0.39) | MMP2MMP1MMP8LTA4HANPEP | |
| SCHEMBL5323550 | 0.82 | MMP2 (0.44) | MMP2MMP1MMP8LTA4HANPEP | |
| SCHEMBL5319409 | 0.80 | MMP2 (0.41) | MMP2MMP1MMP8SLC6A2SLC6A4 | |
| SCHEMBL5403527 | 0.80 | MMP2 (0.43) | MMP2MMP1MMP8MMP13LTA4H | |
| SCHEMBL5319634 | 0.80 | MMP2 (0.43) | MMP2MMP1MMP8MMP13LTA4H | |
| SCHEMBL5320062 | 0.80 | MMP2 (0.43) | MMP2MMP1MMP8MMP13LTA4H | |
| SCHEMBL3868068 | 0.79 | MMP2 (0.42) | MMP2MMP1MMP8MMP13LTA4H | |
| SCHEMBL5378455 | 0.79 | MMP2 (0.42) | MMP2MMP1MMP8TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | claimed |