SCHEMBL5485945

SCHEMBL5485945

CCCCN(CCCC)c1ccc(C(c2ccc(NCCCC#N)cc2)(c2ccc(N(CCCC)CCCC)cc2)c2ccc(N(CCCC)CCCC)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
NR1H2 P55055 8/20 0.37
NR1H3 Q13133 8/20 0.37
ALDH1A1 P00352 1/20 0.37
SLC16A3 O15427 1/20 0.35
SLC16A1 P53985 1/20 0.35
MLYCD O95822 1/20 0.34
HTT P42858 1/20 0.34
NR1I2 O75469 1/20 0.34
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3204518 0.86 GAA (0.39) GAAALDH1A1SLC16A3SLC16A1HTT
SCHEMBL5485948 0.79 CRHR1 (0.39) NR1H2NR1H3ALDH1A1SLC16A3SLC16A1
SCHEMBL3894772 0.74 GAA (0.41) GAAALDH1A1HTTCNR2
SCHEMBL21300769 0.73 LMNA (0.41) GAANR1H2NR1H3ALDH1A1CNR2
SCHEMBL11811681 0.72 ABL1 (0.42) CNR2
SCHEMBL13970832 0.70 LMNA (0.37) GAANR1H2NR1H3ALDH1A1HTT
SCHEMBL5283357 0.70 NR1H2 (0.47) NR1H2NR1H3NR1I2
SCHEMBL19996359 0.69 HDAC3 (0.45) ALDH1A1HTT
SCHEMBL10336985 0.69 NR1H2 (0.39) NR1H2NR1H3SLC16A3SLC16A1NR1I2
SCHEMBL21173008 0.69 MAPT (0.35) GAAALDH1A1SLC16A3SLC16A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7303856-B2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-7150955-B2 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2006-12-19 US disclosed
US-20050037281-A1 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. 2005-02-17 US disclosed
EP-1507171-A2 Light-Sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2005-02-16 EP disclosed
US-20050025946-A1 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJI PHOTO FILM CO., LTD. 2005-02-03 US disclosed
EP-1489460-A2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer Fuji Photo Film Co., Ltd. (JP) 2004-12-22 EP disclosed